Short Name: ATT-ASample required: SerumResult Time: 2 Days Presence of the tissue transglutaminase (tTG) IgA antibody is associated with glutensensitive enteropathies such as celiac disease and dermatitis herpetiformis. tTG IgA antibody concentrations greater than 40 U/mL usually correlate with results of duodenal biopsies consistent with a diagnosis of celiac disease. For antibody concentrations greater or
Read moreShort Name: TPO-AbSample required: SerumResult Time: 1 Days Thyroid peroxidase (TPO) is an enzyme mainly expressed in the thyroid that liberates iodine for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (T4) or triiodothyronine (T3), thyroid hormones. Antibodies against TPO can be evidence of tissue destruction, such as Hashimotos disease, less commonly,
Read moreShort Name: MIC ABSample required: SerumResult Time: 1 Days Anti-thyroid microsomal antibodies are directed against microsomes, which are small cell particles formed from the endoplasmic reticulum of thyroid cells. The body produces microsomal antibodies when these small cell particles escape from damaged thyroid cells. Therefore, thyroid microsomal autoantibodies reflect thyroid cell destruction. Their presence is
Read moreShort Name: THYROGSample required: SerumResult Time: 1 Days Thyroglobulin is a protein produced only in the thyroid gland epithelial cells. Iodine combines with the amino acid tyrosine, which is present in thyroglobulin to produce two thyroid hormones, thyroxine (T4) and triiodothyronine (T3). These hormones are necessary in almost all metabolic activities of the body. Antibodies
Read moreShort Name: THRIIISample required: Citrate PlasmaResult Time: 1 Days Anti-thrombin III is a glycoprotein which is synthesized in the liver and which acts as a physiological inhibitor of thrombin. Its activity is potentiated by heparin. Potentiation of its activity is the principle mechanism by which heparin results in anticoagulation. There are two types of Anti-thrombin
Read moreShort Name: SKESample required: SerumResult Time: 1 Days Anti-skeletal muscle antibodies are present in patients with Myasthenia gravis (MG); an autoimmune disorder that causes the immune systems antibodies to attack skeletal muscles causing extreme muscle weakness and fatigue. These antibodies are specifically directed toward the acetylcholine receptor, located at the neuromuscular junction of skeletal muscles.
Read moreShort Name: ASOTSample required: SerumResult Time: 1 Days ASO is an antibody targeted against streptolysin O; a toxin secreted by Group A streptococci (usually those causing nasopharyngeal infections) or certain Group C and G strains. This test is ordered if a person presents with symptoms suggesting rheumatic fever or glomerulonephritis and has had a recent
Read moreShort Name: ASASample required: SerumResult Time: 3 Days Anti-sperm antibodies are cells that fight against normal, healthy sperm, reducing motility and making it more difficult for sperm to pass through cervical mucus. Antisperm antibodies can also force sperm to clump together, making it difficult for the sperm to fertilize an egg. Anything that results in
Read moreShort Name: ASMASample required: SerumResult Time: 1 Days Anti-Smooth Muscle Antibodies (ASMA) are proteins produced by the bodys immune system that are directed against its own cytoskeletal proteins of the smooth muscle. The production of ASMA is strongly associated with chronic active autoimmune hepatitis but may also be seen in other forms of liver disease
Read moreShort Name: SKIN-AbSample required: SerumResult Time: 2 Days Anti-skin antibodies are responsible for various autoimmune diseases of the epidermis and dermoepidermal junction.There are two distinct types of skin autoantibodies that detect different skin components: anti-basement membrane antibodies associated with bullous pemphigoid, and anti- extracellular matrix antibodies associated with pemphigus. Both these diseases involve blistering of
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